Senior Scientist, II- Analytical Development ( On-site-Worcester, MA)
Company: AbbVie
Location: Worcester
Posted on: July 4, 2025
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Job Description:
Company Description AbbVie's mission is to discover and deliver
innovative medicines and solutions that solve serious health issues
today and address the medical challenges of tomorrow. We strive to
have a remarkable impact on people's lives across several key
therapeutic areas immunology, oncology, neuroscience, and eye care
and products and services in our Allergan Aesthetics portfolio. For
more information about AbbVie, please visit us at www.abbvie.com .
Follow @abbvie on X , Facebook , Instagram , YouTube , LinkedIn and
Tik Tok . Job Description We are seeking a highly motivated Senior
Scientist I to join our Analytical Development team in the Product
Development Science and Technology, Biologics Development Launch
division. Our team is responsible for the development,
qualification, and execution of analytical methods to provide
product and process understanding for biological entities from
discovery through commercial stages. The successful candidate will
be a part of the Biomolecular Interaction Group which is mainly
focused on method development and implementation of various
immunoassays to monitor process impurities and to assess potency of
AbbVies Biologics to support product and process development for
early-phase, late-phase, and commercial programs. Some of the
techniques/methods utilized in the group include 1) ELISAs to
monitor and detect process related impurities; 2) surface plasmon
resonance using Biacore for assessment of antigen binding and
binding of antibody Fc receptors; and 3) qPCR to measure levels of
residual DNA and mycoplasma. The role will involves managing all
analytical aspects of biologics products on the market, overseeing
commercial methods throughout their lifecycle - from method
transfer, performance monitoring, troubleshooting, to method
enhancement. The individual will also play a key role in
establishing commercial product specifications, stability programs,
and regulatory filings. Collaboration with other analytical teams,
process development, global QC, and manufacturing science and
technology groups is a crucial part of this role to meet business
objectives and program milestones. Responsibilities: Partner with
Analytical Development groups to achieve commercial method
readiness using traditional and advanced analytical techniques,
including but not limited to ELISA, bioassays, spectrophotometric
and compendial methods. Participate in cross-functional,
multi-site, global meetings / projects and oversee commercial
analytical method transfer between sites, product/process
investigations, method performance monitoring and troubleshooting.
Establish scientifically sound, analytical lifecycle strategies,
including methods, stability, specification and change management
that meet Health Authority best practices and expectations.
Participate in the preparation and review of technical documents to
ensure global compliance - including validation protocols and
reports, reference standard qualification reports and analytical
test procedures. Author regulatory submissions, support regulatory
inspections and provide scientifically sound responses to agency
deficiency letters. Conduct periodic review of methods and work
with program leads to design, execute remediation experiments, and
implement changes to new or existing commercial methods when
necessary. Qualifications BS or equivalent education in Biology,
Biochemistry, Engineering or related discipline and 8 years of
experience in the biopharmaceutical industry; MS and 6 years
experience; PhD and 3 years experience. Industry experience in
method development, qualification, validation, and method transfer
in support of development and/or commercialization of biological
products. Methods including but not limited to ELISA, western blot,
qPCR, ddPCR, SPR and automation Ability to lead and manage
projects/teams of significant scope and complexity, while meeting
all deliverables and timelines. Ability to think critically and
demonstrate troubleshooting and problem-solving skills. Additional
Information Applicable only to applicants applying to a position in
any location with pay disclosure requirements under state orlocal
law: The compensation range described below is the range of
possible base pay compensation that the Companybelieves ingood
faith it will pay for this role at the timeof this posting based on
the job grade for this position.Individualcompensation paid within
this range will depend on many factors including geographic
location, andwemay ultimatelypay more or less than the posted
range. This range may be modified in thefuture.Salary: $106,500 -
$202,500 We offer a comprehensive package of benefits including
paid time off (vacation, holidays,
sick),medical/dental/visioninsurance and 401(k) to
eligibleemployees. This job is eligible to participate in our
short-term incentiveprograms. This job is eligible to participate
in our long-term incentiveprograms Note: No amount of payis
considered to bewages or compensation until such amount is earned,
vested, anddeterminable.The amount and availability of any
bonus,commission, incentive, benefits, or any other form
ofcompensation and benefitsthat are allocable to a particular
employee remains in the Company's sole andabsolutediscretion unless
and until paid andmay be modified at the Companys sole and absolute
discretion, consistent withapplicable law. AbbVie is an equal
opportunity employer and is committed to operating with integrity,
driving innovation, transforming lives and serving our community.
Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only
- to learn more, visit
https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation,
click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html
Keywords: AbbVie, Westfield , Senior Scientist, II- Analytical Development ( On-site-Worcester, MA), Science, Research & Development , Worcester, Massachusetts